ELISA CHI3L1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Carbohydrate-binding lectin with a preference for chitin. Has no chitinase activity. May play a role in tissue remodeling and in the capacity of cells to respond to and cope with changes in their environment. Plays a role in T-helper cell type 2(Th2) inflammatory response and IL-13-induced inflammation, regµLating allergen sensitization, inflammatory cell apoptosis, dendritic cell accumµLation and M2 macrophage differentiation. Facilitates invasion of pathogenic enteric bacteria into colonic mucosa and lymphoid organs. Mediates activation of AKT1 signaling pathway and subsequent IL8 production in colonic epithelial cells. RegµLates antibacterial responses in lung by contributing to macrophage bacterial killing, controlling bacterial dissemination and aµgmenting host tolerance. Also regµLates hyperoxia-induced injury, inflammation and epithelial apoptosis in lung. Immunogen:chitinase 3-like 1(cartilage glycoprotein-39) Synonyms:39 kDa synovial protein, ASRT7, Cartilage glycoprotein 39, CGP 39, CHI3L1, Chitinase 3 like protein 1, GP 39, GP39, HC gp39, hCGP 39, HCGP 3P, YKL 40, YKL40, YYL 40 Observed MW:43 kDa Uniprot ID:P36222 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC Recommended dilution:IHC: 1:50 - 1:200 Gene ID:1116 Research Area:Signal Transduction, immunology