ELISA BCL2 anti-

Quantity:100µg Purification:Protein A+G purification Form:liquid Purity:?95% as determined by SDS-PAGE Host:Mouse Clonality:monoclonal Clone ID:8A10 Isotype:IgG2a Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. RegµLates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor(APAF-1). May attenuate inflammation by impairing NLRP1-inflammasome activation, hence CASP1 activation and IL1B release(PubMed:17418785). Immunogen:B-cell CLL/lymphoma 2 Synonyms:Apoptosis regµLator Bcl 2, B cell CLL/lymphoma 2, BCL2, Oncogene B cell leukemia 2 Observed MW:26 kDa Uniprot ID:P10415 Reactivity: Tested Application:ELISA, WB, IP, IHC Recommended dilution:WB: 1:1000-1:10000; IP: 1:500-1:5000; IHC: 1:100-1:2000 Gene ID:596 Research Area:Neuroscience, Cancer, Immunology, CardiovascµLar