ELISA BAX anti-
Quantity:100µg
Purification:Protein A+G purification
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Mouse
Clonality:monoclonal
Clone ID:5F4
Isotype:IgG2a
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Accelerates programmed cell death by binding to, and antagonizing the apoptosis repressor BCL2 or its adenovirus homolog E1B 19k protein. Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis. Promotes activation of CASP3, and thereby apoptosis.
Immunogen:BCL2-associated X protein
Synonyms:BCL2L4
Observed MW:21 kDa
Uniprot ID:Q07812
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB,IHC,IF
Recommended dilution:WB: 1:1000-1:10000; IHC: 1:400-1:1000; IF: 1:50-1:500
Gene ID:581
Research Area:Neuroscience, Cancer, Developmental biology