ELISA BAX anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:BAX, also named as BCL2L4, is a pro-apoptotic member of the Bcl-2 protein family, which plays a pivotal role in controlling cell life and death. Bax largely localizes to the cytoplasm of healthy cells, but accumµLates on the outer mitochondrial membrane upon apoptosis induction(PMID: 9108035). BAX can commit a cell to apoptosis by translocation from the cytosol to the mitochondria and permeabilization of the outer mitochondrial membrane, which leads to the release of cytochrome c from mitochondria(PMID: 21763611). The expression of BAX is upregµLated by the tumor suppressor protein p53, and BAX has been shown to be involved in p53-mediated apoptosis(PMID: 8183579). Immunogen:BCL2-associated X protein Synonyms:BCL2L4,Apoptosis regµLator BAX, BAX Observed MW:21 kDa Uniprot ID:Q07812 Reactivity:, Mouse, Rat, Rabbit, Sheep Tested Application:ELISA, WB, IHC, IP, FC Recommended dilution:WB: 1:1000-1:10000; IP: 1:1000-1:10000; IHC: 1:20-1:200 Gene ID:581 Research Area:Neuroscience, Cancer, Developmental biology