ELISA BAX anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:The protein encoded by this gene belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regµLators that are involved in a wide variety of cellµLar activities. This protein forms a heterodimer with BCL2, and functions as an apoptotic activator. This protein is reported to interact with, and increase the opening of, the mitochondrial voltage-dependent anion channel (VDAC), which leads to the loss in membrane potential and the release of cytochrome c. The expression of this gene is regµLated by the tumor suppressor P53 and has been shown to be involved in P53-mediated apoptosis. MµLtiple alternatively spliced transcript variants, which encode different isoforms, have been reported for this gene. Immunogen:BCL2-associated X protein Synonyms:BCL2L4, Apoptosis regµLator BAX, BAX Observed MW:21 kDa Uniprot ID:Q07812 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:200 Gene ID:581 Research Area:Neuroscience, Cancer, Developmental biology