ELISA BANP anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Controls V(D)J recombination during T-cell development by repressing T-cell receptor(TCR) beta enhancer function. Binds to scaffold/matrix attachment region beta(S/MARbeta), an ATC-rich DNA sequence located upstream of the TCR beta enhancer. Represses cyclin D1 transcription by recruiting HDAC1 to its promoter, thereby diminishing H3K9ac, H3S10ph and H4K8ac levels. Promotes TP53 'Ser-15' phosphorylation and nuclear accumµLation, which causes cell cycle arrest(By similarity).
Immunogen:BTG3 associated nuclear protein
Synonyms:BANP, BEND1, Protein BANP, SMAR1, SMARBP1
Observed MW:56kd
Uniprot ID:Q8N9N5
Reactivity:, Mouse, Rat
Tested Application:ELISA, IHC, WB
Recommended dilution:WB: 1:500-1:1000; IHC: 1:50-1:500
Gene ID:54971
Research Area:Metabolism, Developmental biology