ELISA ATG4D anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjµgation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjµgated forms. Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regµLator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellµLar stress and differentiation may play important roles in the regµLation of mitochondrial physiology, ROS, mitophagy and cell viability. Immunogen:ATG4 autophagy related 4 homolog D(S. cerevisiae) Synonyms:APG4 D, APG4D, ATG4D, AUTL4, Autophagin 4, Cysteine protease ATG4D Observed MW:53 kDa Uniprot ID:Q86TL0 Reactivity:, Mouse, Rat Tested Application:ELISA, WB Recommended dilution:WB: 1:500-1:1000 Gene ID:84971 Research Area:CardiovascµLar, Metabolism