ELISA ATG4B anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Cysteine protease required for the cytoplasm to vacuole transport(Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3, GABARAPL1, GABARAPL2 and GABARAP, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjµgation to phosphatidylethanolamine(PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjµgated forms.
Immunogen:ATG4 autophagy related 4 homolog B(S. cerevisiae)
Synonyms:APG4B, AUTL1, KIAA0943
Observed MW:44 kDa
Uniprot ID:Q9Y4P1
Reactivity:, Mouse, Rat
Tested Application:ELISA, WB, IHC, IP
Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:2000 ; IHC: 1:20-1:200
Gene ID:23192
Research Area:CardiovascµLar, Metabolism