ELISA CRTC3 anti-

Quantity :50µL Clone Number:10G3 Aliases:CREB-regµLated transcription coactivator 3 (Transducer of regµLated cAMP response element-binding protein 3) (TORC-3) (Transducer of CREB protein 3), CRTC3, TORC3 Product Type:Recombinant Antibody Immunogen Species:Homo sapiens () UniProt ID:Q6UUV7 Immunogen:A syntheQuantityd peptide derived from CRTC3 Raised in: Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:50-1:200 Background:Transcriptional coactivator for CREB1 which activates transcription throµgh both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. RegµLates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). {ECO:0000269|PubMed:14506290, ECO:0000269|PubMed:15454081, ECO:0000269|PubMed:15466468, ECO:0000269|PubMed:16817901, ECO:0000269|PubMed:16980408, ECO:0000269|PubMed:17210223, ECO:0000269|PubMed:17644518}. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CRTC3 Research Areas:Epigenetics and Nuclear Signaling; Microbiology