ELISA Phospho-MAPT (S324) anti-

Quantity :50µL Clone Number:4E8 Aliases:MicrotubµLe-associated protein tau, Neurofibrillary tangle protein, Paired helical filament-tau, PHF-tau, MAPT, MAPTL, MTBT1, TAU Product Type:Recombinant Antibody Immunogen Species: UniProt ID:P10636 Immunogen:A syntheQuantityd peptide derived from Phospho-MAPT (S324) Raised in: Reactivity: Tested Applications:ELISA, IF; Recommended dilution: IF:1:20-1:200 Background:Promotes microtubµLe assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubµLes while the N-terminus binds neural plasma membrane components, sµggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by TAU/MAPT localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization. Clonality:Monoclonal Isotype:Rabbit IgG Purification Method:Affinity-chromatography Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:MAPT Research Areas:Neuroscience