ELISA CLDN8 anti-

Quantity :50µL Clone Number: Aliases:Claudin 8 antibody; Claudin-8 antibody; CLD8_ antibody; Cldn8 antibody; Epididymis secretory protein Li 79 antibody; HEL S 79 antibody; OTTHUMP00000101915 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P56748 Immunogen:Synthetic peptide of CLDN8 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely throµgh the paracellµLar space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This protein plays important roles in the paracellµLar cation barrier of the distal renal tubµLe, and in the paracellµLar barrier to prevent sodium back-leakage in distal colon. Differential expression of this gene has been observed in colorectal carcinoma and renal cell tumors, and along with claudin-7, is an immunohistochemical marker for the differential diagnosis of chromophobe renal cell carcinoma and renal oncocytoma. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CLDN8 Research Areas:Signal transduction