ELISA BIN1 anti-

Quantity :50µL Clone Number: Aliases:AMPH 2 antibody; AMPH2 antibody; Amphiphysin 2 antibody; Amphiphysin II antibody; Amphiphysin like protein antibody; amphiphysin-like antibody; Amphiphysin-like protein antibody; AMPHL antibody; Bin1 antibody; BIN1_ antibody; Box Dependant MYC Interacting Protein 1 antibody; Box-dependent myc-interacting protein 1 antibody; Bridging integrator 1 antibody; DKFZp547F068 antibody; MGC10367 antibody; MGC105358 antibody; Myc box dependent interacting protein 1 antibody; Myc box-dependent-interacting protein 1 antibody; SH3P9 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O00499 Immunogen:Fusion protein of BIN1 Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:1000-1:5000, IHC:1:50-1:200 Background:This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse sµggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene resµLts in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BIN1 Research Areas:Epigenetics and Nuclear Signaling;Cancer;Cell biology;Microbiology