ELISA BCL2L1 (Ab-62) anti-

Quantity :100µL Clone Number: Aliases:Apoptosis regµLator Bcl X antibody; Apoptosis regµLator Bcl-X antibody; Apoptosis regµLator BclX antibody; B cell lymphoma 2 like antibody; B2CL1_ antibody; Bcl 2 like 1 protein antibody; Bcl X antibody; Bcl xL antibody; BCL XL/S antibody; Bcl xS antibody; Bcl-2-like protein 1 antibody; Bcl2 Like 1 antibody; Bcl2 related gene antibody; Bcl2-L-1 antibody; BCL2L antibody; Bcl2l1 antibody; BCLX antibody; BclXL antibody; BclXs antibody; DKFZp781P2092 antibody; PPP1R52 antibody; Protein phosphatase 1 regµLatory subunit 52 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q07817 Immunogen:Peptide sequence around aa.60~64 (A-D-S-P-A) derived from BCL-XL Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:1000 Background:Potent inhibitor of cell death. Isoform Bcl-X(L) anti-apoptotic activity is inhibited by association with SIVA isoform 1. Inhibits activation of caspases By similarity. Appears to regµLate cell death by blocking the voltage-dependent anion channnel (VDAC) by binding to it and preventing the release of the caspase activator, cytochrome c, from the mitochondrial membrane. The Bcl-X(S) isoform promotes apoptosis. Basu A, et.al.( 2003) Mar 13; 538(1-3): 41-7 Cheng E.H.-Y. et.al. (1996) Nature 379:554-556. Sattler M. et.al. (1997), Science 275:983-986. Muchmore S.W.et.al (1996).Nature 381:335-341 Yu J., Zhang L. Mol. (2001)Cell 7:673-682 Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BCL2L1 Research Areas:Cancer;Cell biology;Metabolism;Signal transduction