ELISA ARL6 anti-

Quantity :50µL Clone Number: Aliases:ADP ribosylation factor like 6 antibody; ADP ribosylation factor like protein 6 antibody; ADP-ribosylation factor-like protein 6 antibody; Arl6 antibody; ARL6_ antibody; Bardet Biedl syndrome 3 protein antibody; Bardet-Biedl syndrome 3 protein antibody; BBS3 antibody; MGC32934 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9H0F7 Immunogen:Recombinant ADP-ribosylation factor-like protein 6 protein (1-186AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200 Background:Involved in membrane protein trafficking at the base of the ciliary organelle. Mediates recruitment onto plasma membrane of the BBSome complex which woµLd constitute a coat complex required for sorting of specific membrane proteins to the primary cilia (PubMed:20603001). Together with BBS1, is necessary for correct trafficking of PKD1 to primary cilia (By similarity). Together with the BBSome complex and LTZL1, controls SMO ciliary trafficking and contributes to the sonic hedgehog (SHH) pathway regµLation (PubMed:22072986). May regµLate cilia assembly and disassembly and subsequent ciliary signaling events such as the Wnt signaling cascade (PubMed:20207729). Isoform 2 may be required for proper retinal function and organization (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:Antigen Affinity Purified Conjµgate:Non-conjµgated Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3. Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ARL6 Research Areas:Signal transduction