ELISA CHAC1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Blocks Notch protein antibody; Botch antibody; Cation transport regµLator like protein 1 antibody; Cation transport regµLator-like protein 1 antibody; ChaC antibody; ChaC cation transport regµLator homolog 1 antibody; ChaC cation transport regµLator like 1 antibody; chac1 antibody; CHAC1_ antibody; Gamma GCT acting on glutathione homolog 1 antibody; Gamma-GCG 1 antibody; Glutathione-specific gamma-glutamylcyclotransferase 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9BUX1 Immunogen:Recombinant Glutathione-specific gamma-glutamylcyclotransferase 1 protein (43-264AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Catalyzes the cleavage glutathione into 5-oxoproline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides. Glutathione depletion is an important factor for apoptosis initiation and execution (PubMed:23070364). Acts as a pro-apoptotic component of the unfolded protein response pathway by mediating the pro-apoptotic effects of the ATF4-ATF3-DDIT3/CHOP cascade (PubMed:19109178). Negative regµLator of Notch signaling pathway involved in embryonic neurogenesis: acts by inhibiting Notch cleavage by furin, maintaining Notch in an immature inactive form, thereby promoting neurogenesis in embryos (PubMed:22445366). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CHAC1 Research Areas:Cell biology