ELISA ATP8A2 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:AT8A2_ antibody; ATP antibody; Atp8a2 antibody; ATPase aminophospholipid transporter class I type 8A member 2 antibody; ATPase aminophospholipid transporter like class I type 8A member 2 antibody; ATPase class I type 8A member 2 antibody; ATPase phospholipid transporting 8A2 antibody; ATPIB antibody; CAMRQ4 antibody; EC=3.6.3.1 antibody; IB antibody; mL-1 antibody; mL1 antibody; P4 ATPase flippase complex alpha subunit ATP8A2 antibody; Probable phospholipid-transporting ATPase IB antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NTI2 Immunogen:Recombinant Phospholipid-transporting ATPase IB protein (358-570AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecµLes. Reconstituted to liposomes, the ATP8A2:TMEM30A flippase complex predomiminantly transports phosphatidylserine (PS) and to a lesser extent phosphatidylethanolamine (PE). Proposed to function in the generation and maintenance of phospholipid asymmetry in photoreceptor disk membranes and neuronal axon membranes. May be involved in vesicle trafficking in neuronal cells. Involved in regµLation of neurite outgrowth; acting in synergy with TMEM30A. Required for normal visual and auditory function; involved in photoreceptor and inner ear spiral ganglion cell survival. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ATP8A2 Research Areas:Others