ELISA CPNE1 Antibody, FITC
Quantity :50µL
Clone Number:
Aliases:Copine 1 antibody; Copine I antibody; Copine-1 antibody; Copine1 antibody; CopineI antibody; COPN 1 antibody; COPN1 antibody; CPN 1 antibody; CPN1 antibody; CPNE 1 antibody; CPNE1 antibody; CPNE1_ antibody; MGC1142 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q99829
Immunogen:Recombinant Copine-1 protein (326-537AA)
Raised in:Rabbit
Reactivity:
Tested Applications:
Background:Calcium-dependent phospholipid-binding protein that plays a role in calcium-mediated intracellµLar processes (PubMed:14674885). Involved in the TNF-alpha receptor signaling pathway in a calcium-dependent manner (PubMed:14674885). Exhibits calcium-dependent phospholipid binding properties (PubMed:9430674, PubMed:19539605). Plays a role in neuronal progenitor cell differentiation; induces neurite outgrowth via a AKT-dependent signaling cascade and calcium-independent manner (PubMed:23263657, PubMed:25450385). May recruit target proteins to the cell membrane in a calcium-dependent manner (PubMed:12522145). May function in membrane trafficking (PubMed:9430674). Involved in TNF-alpha-induced NF-kappa-B transcriptional repression by inducing endoprotease processing of the transcription factor NF-kappa-B p65/RELA subunit (PubMed:18212740). Also induces endoprotease processing of NF-kappa-B p50/NFKB1, p52/NFKB2, RELB and REL (PubMed:18212740).
Clonality:Polyclonal
Isotype:IgG
Purification Method:Antigen Affinity Purified
Conjµgate:FITC
Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CPNE1
Research Areas:Signal transduction
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