ELISA CHST14 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:2600016L03Rik antibody; ATCS antibody; Carbohydrate (N acetylgalactosamine 4 0) sµLfotransferase 14 antibody; Carbohydrate sµLfotransferase 14 antibody; CHST14 antibody; CHSTE_ antibody; D4ST-1 antibody; D4st1 antibody; Dermatan 4-sµLfotransferase 1 antibody; hD4ST1 antibody; RP23-286G12.2 antibody; UNQ1925/PRO4400 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8NCH0 Immunogen:Recombinant Carbohydrate sµLfotransferase 14 protein (70-133AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Catalyzes the transfer of sµLfate to position 4 of the N-acetylgalactosamine (GalNAc) residue of dermatan sµLfate. Plays a pivotal role in the formation of 4-0-sµLfated IdoA blocks in dermatan sµLfate. Transfers sµLfate to the C-4 hydroxyl of beta1,4-linked GalNAc that is substituted with an alpha-linked iduronic acid (IdoUA) at the C-3 hydroxyl. Transfers sµLfate more efficiently to GalNAc residues in -IdoUA-GalNAc-IdoUA- than in -GlcUA-GalNAc-GlcUA-sequences. Has preference for partially desµLfated dermatan sµLfate. Addition of sµLfate to GalNAc may occur immediately after epimerization of GlcUA to IdoUA. Appears to have an important role in the formation of the cerebellar neural network during postnatal brain development. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CHST14 Research Areas: