ELISA DDX42 Antibody, HRP

Quantity :50µg Clone Number: Aliases:DDX42ATP-dependent RNA helicase DDX42 antibody; EC 3.6.4.13 antibody; DEAD box protein 42 antibody; RNA helicase-like protein antibody; RHELP antibody; RNA helicase-related protein antibody; RNAHP antibody; SF3b DEAD box protein antibody; Splicing factor 3B-associated 125 kDa protein antibody; SF3b125 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86XP3 Immunogen:Recombinant ATP-dependent RNA helicase DDX42 protein (519-819AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:ATP-dependent RNA helicase. Binds to partially double-stranded RNAs (dsRNAs) in order to unwind RNA secondary structures. Unwinding is promoted in the presence of single-strand binding proteins. Mediates also RNA duplex formation thereby displacing the single-strand RNA binding protein. ATP and ADP modµLate its activity: ATP binding and hydrolysis by DDX42 triggers RNA strand separation, whereas the ADP-bound form of the protein triggers annealing of complementary RNA strands. Involved in the survival of cells by interacting with TP53BP2 and thereby counteracting the apoptosis-stimµLating activity of TP53BP2. Relocalizes TP53BP2 to the cytoplasm. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DDX42 Research Areas:Epigenetics and Nuclear Signaling