ELISA CRTC2 Antibody, HRP

Quantity :50µg Clone Number: Aliases:CREB regµLated transcription coactivator 2 antibody; CREB-regµLated transcription coactivator 2 antibody; CRTC2 antibody; CRTC2_ antibody; RP11-422P24.6 antibody; TORC-2 antibody; torc2 antibody; Transducer of CREB protein 2 antibody; Transducer of regµLated cAMP response element-binding protein antibody; Transducer of regµLated cAMP response element-binding protein (CREB) 2 antibody; Transducer of regµLated cAMP response element-binding protein 2 antibody; Transducer of regµLated CREB protein 2 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q53ET0 Immunogen:Recombinant CREB-regµLated transcription coactivator 2 protein (180-372AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcriptional coactivator for CREB1 which activates transcription throµgh both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 \'Ser-133\' phosphorylation. Enhances the interaction of CREB1 with TAF4. RegµLates gluconeogenesis as a component of the LKB1/AMPK/TORC2 signaling pathway. RegµLates the expression of specific genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CRTC2 Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; Cancer; Metabolism; Signal transduction