ELISA CNTN1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:CNTN 1 antibody; CNTN antibody; Cntn1 antibody; CNTN1_ antibody; Contactin-1 antibody; Contactin1 antibody; F3 antibody; F3cam antibody; Glycoprotein gp135 antibody; gp 135 antibody; GP135 antibody; MYPCN antibody; Neural cell surface protein F3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q12860 Immunogen:Recombinant Contactin-1 protein (686-866AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation throµgh the released notch intracellµLar domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repµLsion of neurons and an inhibition of neurite outgrowth (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CNTN1 Research Areas:Neuroscience