ELISA CKAP5 Antibody, HRP

Quantity :50µg Clone Number: Aliases:CKAP5 antibody; KIAA0097Cytoskeleton-associated protein 5 antibody; Colonic and hepatic tumor overexpressed gene protein antibody; Ch-TOG antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q14008 Immunogen:Recombinant Cytoskeleton-associated protein 5 protein (1802-2019AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Binds to the plus end of microtubµLes and regµLates microtubµLe dynamics and microtubµLe organization. Acts as processive microtubµLe polymerase. Promotes cytoplasmic microtubµLe nucleation and elongation. Plays a major role in organizing spindle poles. In spindle formation protects kinetochore microtubµLes from depolymerization by KIF2C and has an essential role in centrosomal microtubµLe assembly independently of KIF2C activity. Contributes to centrosome integrity. Acts as component of the TACC3/ch-TOG/clathrin complex proposed to contribute to stabilization of kinetochore fibers of the mitotic spindle by acting as inter-microtubµLe bridge. The TACC3/ch-TOG/clathrin complex is required for the maintenance of kinetochore fiber tension (PubMed:23532825). Enhances the strength of NDC80 complex-mediated kinetochore-tip microtubµLe attachments (PubMed:27156448). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CKAP5 Research Areas:Cancer; Cell biology; Tags & Cell Markers; Signal transduction