ELISA CIT anti-

Quantity :100µL Clone Number: Aliases:CIT antibody; CRIK antibody; KIAA0949 antibody; STK21Citron Rho-interacting kinase antibody; CRIK antibody; EC 2.7.11.1 antibody; Serine/threonine-protein kinase 21 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O14578 Immunogen:SyntheQuantityd peptide derived from internal of CTRO. Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; IHC:1:50-1:100 Background:Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Plays an important role in the regµLation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/mLC2. Nagase T., DNA Res. 6:63-70(1999). Scherer S.E., Nature 440:346-351(2006). Gruneberg U., J. Cell Biol. 172:363-372(2006). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CIT Research Areas:Neuroscience;Cell biology;Signal transduction