ELISA CLK1 anti-

Quantity :100µL Clone Number: Aliases:CDC like kinase 1 antibody; CDC-like kinase 1 antibody; CDC28/CDC2 like kinase antibody; CLK antibody; CLK/STY antibody; Clk1 antibody; CLK1_ antibody; Dual specificity protein kinase CLK1 antibody; Protein tyrosine kinase STY antibody; STY antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P49759 Immunogen:SyntheQuantityd peptide derived from internal of CLK1. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB, IF; WB:1:500-1:3000, IF:1:100-1:500 Background:Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine-rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regµLatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. RegµLates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA. Johnson K.W., J. Biol. Chem. 266:3402-3407(1991). Hanes J.J., J. Mol. Biol. 244:665-672(1994). Olsen J.V., Cell 127:635-648(2006). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CLK1 Research Areas:Epigenetics and Nuclear Signaling;Signal transduction