ELISA CHRNA10 anti-

Quantity :100µL Clone Number: Aliases:Acetylcholine receptor, neuronal nicotinic, alpha-10 subunit antibody; ACH10_ antibody; Alpha 10 nAChR antibody; Cholinergic receptor nicotinic alpha 10 antibody; Cholinergic receptor, neuronal nicotinic, alpha polypeptide 10 antibody; Cholinergic receptor, nicotinic, alpha polypeptide 10 antibody; CHRNA 10 antibody; CHRNA10 antibody; NACHR alpha 10 antibody; NACHR alpha-10 antibody; NACHRA10 antibody; Neuronal acetylcholine receptor protein subunit alpha 10 antibody; Neuronal acetylcholine receptor subunit alpha-10 antibody; Nicotinic acetylcholine receptor subunit alpha 10 antibody; Nicotinic acetylcholine receptor subunit alpha-10 antibody; OTTHUMP00000013620 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9GZZ6 Immunogen:SyntheQuantityd peptide derived from C-terminal of CHRNA10. Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Ionotropic receptor with a probable role in the modµLation of auditory stimµLi. Agonist binding may induce an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. The channel is permeable to a range of divalent cations including calcium, the influx of which may activate a potassium current which hyperpolarizes the cell membrane. In the ear, this may lead to a reduction in basilar membrane motion, altering the activity of auditory nerve fibers and reducing the range of dynamic hearing. This may protect against acoustic trauma. Sgard F., Mol. Pharmacol. 61:150-159(2002). Lustig L.R., Genomics 73:272-283(2001). Vandenberk I., Submitted (NOV-2000) to the EMBL/GenBank/DDBJ databases. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CHRNA10 Research Areas:Neuroscience;Signal transduction