ELISA ATXN1 anti-

Quantity :50µL Clone Number: Aliases:alternative ataxin1 antibody; Ataxin-1 antibody; ATX1 antibody; ATX1_ antibody; Atxn1 antibody; D6S504E antibody; OTTHUMP00000016065 antibody; SCA1 antibody; Spinocerebellar ataxia type 1 protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P54253 Immunogen:Fusion protein of ATXN1 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200 Background:The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ATXN1 Research Areas:Epigenetics and Nuclear Signaling?Neuroscience