ELISA BFAR anti-

Quantity :50µL Clone Number: Aliases:BFAR antibody; BAR antibody; RNF47Bifunctional apoptosis regµLator antibody; RING finger protein 47 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NZS9 Immunogen:Synthetic peptide of BFAR Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:A novel protein, BAR, for bifunctional apoptosis regµLator, contains domains that enable it to interact with components of both major apoptosis pathways, where it negatively regµLates apoptotic signaling. Like the other anti-apoptosis proteins Bap31 and FLIP, BAR contains a DED-like domain that is capable of suppressing apoptosis mediated at the receptor level. In addition, BAR contains a domain that also enables it to interact with the mitochondrial Bcl-2 family of proteins. The presence of these various RING, SAM, DED and TM domains sµggests that BAR may serve as a scaffold protein that integrates signaling components of the cells apoptosis-regµLatory machinery. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BFAR Research Areas:Cell biology