ELISA CREB1 (Ab-133) anti-

Quantity :100µL Clone Number: Aliases:Active transcription factor CREB antibody; cAMP response element binding protein 1 antibody; cAMP response element binding protein antibody; cAMP responsive element binding protein 1 antibody; cAMP-responsive element-binding protein 1 antibody; CREB antibody; CREB-1 antibody; CREB1 antibody; CREB1_ antibody; Cyclic AMP-responsive element-binding protein 1 antibody; MGC9284 antibody; OTTHUMP00000163864 antibody; OTTHUMP00000163865 antibody; OTTHUMP00000206660 antibody; OTTHUMP00000206662 antibody; OTTHUMP00000206667 antibody; Transactivator protein antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P16220 Immunogen:Peptide sequence around aa. 131~135 (R-P-S-Y-R) derived from CREB. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IHC; WB:1:500-1:1000, IHC:1:50-1:200 Background:This protein binds the cAMP response element (CRE), a sequence present in many viral and cellµLar promoters. CREB stimµLates transcription on binding to the CRE. Transcription activation is enhanced by the TORC coactivators which act independently of Ser-133 phosphorylation. Implicated in synchronization of circadian rhythmicity. Xing J, et al. (1998) Mol Cell Biol 18(4): 1946-55. Tan Y, et al.( 1996) EMBO J; 15(17): 4629-42. Hao, M. et al. (1996) J. Biol. Chem. 271, 29380-29385. Mayo LD, et al. (2001) Biol Chem; 276(27): 25184-9. Lu, H. et al. (1997) Mol. Cell. Biol. 17, 5923-5934. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CREB1 Research Areas:Epigenetics and Nuclear Signaling;Immunology