ELISA ARL6IP1 anti-

Quantity :50µL Clone Number: Aliases:ADP ribosylation factor like 6 interacting protein antibody; ADP-ribosylation factor-like protein 6-interacting protein 1 antibody; Aip-1 antibody; Aip1 antibody; AR6P1_ antibody; ARL-6-interacting protein 1 antibody; ARL6 interacting protein 1 antibody; ARL6IP antibody; Arl6ip1 antibody; ARMER antibody; KIAA0069 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q15041 Immunogen:Fusion protein of ARL6IP1 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:25-1:100 Background:ARMER (apoptotic regµLator in the membrane of the endoplasmic reticµLum), also known as ADP-ribosylation-like factor 6-interacting protein 1 (ARL6IP1 or AIP1), is a mµLti-pass membrane protein that belongs to the Ras superfamily. It is expressed in brain, thymus, lung, bone marrow and, to a lesser extent, in spleen, kidney and liver. ARMER is not found in the heart and is found predominantly in early myeloid progenitor cells localizing to the intracytoplasmic membranes. It interacts with ARL6, inhibits caspase-9 activity by inhibiting proteolysis of downstream substrates (including LEHD-AFC, vimentin and caspase-3) and is down-regµLated during myeloid differentiation. ARMER may play a role in membrane trafficking, protein transport or cell signaling during hematopoietic maturation. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ARL6IP1 Research Areas:Cell biology