ELISA CERS6 anti-

Quantity :50µL Clone Number: Aliases:Ceramide synthase 6 antibody; CerS 6 antibody; CERS5 antibody; CerS6 antibody; LAG1 homolog ceramide synthase 6 antibody; LAG1 longevity assurance homolog 6 antibody; LASS 6 antibody; Lass6 antibody; LASS6_ antibody; Longevity assurance homolog 6 antibody; MGC129949 antibody; MGC129950 antibody; T1L antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q6ZMG9 Immunogen:Synthetic peptide of CERS6 Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200 Background:The LASS (longevity assurance homolog) family members are highly conserved from yeasts to mammals. Six members of this family of proteins have been characterized (LASS1, LASS2, LASS3, LASS4, LASS5 and LASS6) and they all are involved in sphingolipid synthesis. LASS6 is a widely expressed 384 amino acid endoplasmic reticµLum, mµLti-pass membrane protein. On the luminal side of the endoplasmic reticµLum membrane, the N-terminal asparagine residue is glycosylated. In cells deficient for CLN9, LASS6 corrects growth and apoptosis, and increases the levels of short ceramide species, such as C14:0- and C16:0-ceramides. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CERS6 Research Areas:Cancer;Metabolism;Signal transduction