ELISA CTDSP1 anti-
Quantity :100µL
Clone Number:
Aliases:Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 antibody; CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1 antibody; CTD small phosphatase 1 antibody; CTDS1_ antibody; CTDSP1 antibody; NIF3 antibody; NLI IF antibody; NLI interacting factor 3 antibody; NLI-IF antibody; NLI-interacting factor 3 antibody; NLIIF antibody; Nuclear LIM interactor interacting factor 3 antibody; Nuclear LIM interactor-interacting factor 3 antibody; SCP1 antibody; Small C-terminal domain phosphatase 1 antibody; Small CTD phosphatase 1 antibody
Product Type:Polyclonal Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:Q9GZU7
Immunogen:SyntheQuantityd peptide derived from N-terminal of CTDSP1.
Raised in:Rabbit
Reactivity:
Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100
Background:Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regµLates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Marquet S., Mamm. Genome 11:755-762(2000).
Yeo M., J. Biol. Chem. 278:26078-26085(2003).
Hillier L.W., Nature 434:724-731(2005)
Clonality:Polyclonal
Isotype:IgG
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Conjµgate:Non-conjµgated
Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:CTDSP1
Research Areas:Epigenetics and Nuclear Signaling;Signal transduction
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