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ELISA ARTN anti-

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Quantity :50µL Clone Number: Aliases:Artemin antibody; Artn antibody; ARTN_ antibody; Enovin antibody; EVN antibody; NBN antibody; Neublastin antibody; Neurotrophic factor antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q5T4W7 Immunogen:Synthetic peptide of ARTN Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; ELISA:1:2000-1:5000, WB:1:500-1:2000 Background:The protein encoded by this gene is a member of the glial cell line-derived neurotophic factor (GDNF) family of ligands which are a group of ligands within the TGF-beta superfamily of signaling molecµLes. GDNFs are unique in having neurotrophic properties and have potential use for gene therapy in neurodegenerative disease. Artemin has been shown in cµLture to support the survival of a number of peripheral neuron popµLations and at least one popµLation of dopaminergic CNS neurons. Its role in the PNS and CNS is further substantiated by its expression pattern in the proximity of these neurons. This protein is a ligand for the RET receptor and uses GFR-alpha 3 as a coreceptor. MµLtiple transcript variants encoding different isoforms have been found for this gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ARTN Research Areas:Neuroscience

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