ELISA ATF3 anti-

Quantity :100µL Clone Number: Aliases:Activating transcription factor 3 antibody; ATF3 antibody; ATF3_ antibody; ATF3deltaZip2 antibody; ATF3deltaZip2c antibody; ATF3deltaZip3 antibody; cAMP dependent transcription factor ATF3 antibody; cAMP-dependent transcription factor ATF-3 antibody; Cyclic AMP dependent transcription factor ATF3 antibody; Cyclic AMP-dependent transcription factor ATF-3 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P18847 Immunogen:SyntheQuantityd peptide derived from internal of ATF3. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellµLar promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters. Chen B.P.C., J. Biol. Chem. 269:15819-15826(1994). Hai T., Genes Dev. 3:2083-2090(1989). Hillman R.T., Genome Biol. 5:RESEARCH008.1-RESEARCH008.16(2004). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ATF3 Research Areas:Epigenetics and Nuclear Signaling;Cancer