ELISA DCTN4 anti-

Quantity :50µL Clone Number: Aliases:DCTN 4 antibody; Dctn4 antibody; DCTN4_ antibody; Dynactin 4 (p62) antibody; Dynactin 4 antibody; Dynactin p62 subunit antibody; Dynactin subunit 4 antibody; Dynactin subunit p62 antibody; Dynactin4 antibody; p62 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9UJW0 Immunogen:Fusion protein of DCTN4 Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:100-1:300 Background:Dynactin is a mµLtisubunit complex and a required cofactor for most, or all, of the cellµLar processes powered by the microtubµLe-based motor cytoplasmic dynein Dynactin contains a short actin-related protein 1 (Arp1) filament with capZ at the barbed end and p62 at the pointed end The p62 subunit is an integral component of 20 S dynactin with a highly conserved cysteine-rich motif that interacts directly with Arp1. Dynactin p62 has a punctate cytoplasmic distribution as well as centrosomal distribution typical of dynactin In addition, Dynactin p62 is distributed in the nucleus at very high expression levels Due to the structural composition of dynactin, the p62 subunit is implicated in Arp1 pointed-end binding and in linking dynein and dynactin to the cortical cytoskeleton. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DCTN4 Research Areas:Signal transduction