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ELISA CH25H Antibody, FITC

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Quantity :50µg Clone Number: Aliases:CH25H antibody; Cholesterol 25-hydroxylase antibody; EC 1.14.99.38 antibody; Cholesterol 25-monooxygenase antibody; h25OH antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O95992 Immunogen:Recombinant Cholesterol 25-hydroxylase protein (142-272AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Catalyzes the formation of 25-hydroxycholesterol from cholesterol, leading to repress cholesterol biosynthetic enzymes (PubMed:9852097). Plays a key role in cell positioning and movement in lymphoid tissues: 25-hydroxycholesterol is an intermediate in biosynthesis of 7-alpha,25-dihydroxycholesterol (7-alpha,25-OHC), an oxysterol that acts as a ligand for the G protein-coupled receptor GPR183/EBI2, a chemotactic receptor for a number of lymphoid cells. May play an important role in regµLating lipid metabolism by synthesizing a corepressor that blocks sterol regµLatory element binding protein (SREBP) processing. In testis, production of 25-hydroxycholesterol by macrophages may play a role in Leydig cell differentiation. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:CH25H Research Areas:Cancer; CardiovascµLar; Cell biology; Metabolism

431.60 € 431.6 EUR 431.60 € Tax Excluded

431.60 € Tax Excluded

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