ELISA BANF1 Antibody, FITC

Quantity :50µg Clone Number: Aliases:BAF antibody; BAF_ antibody; BANF 1 antibody; BANF1 antibody; Barrier to autointegration factor 1 antibody; Barrier to autointegration factor antibody; Barrier-to-autointegration factor antibody; BCRG 1 antibody; BCRG1 antibody; BCRP 1 antibody; BCRP1 antibody; Breakpoint cluster region protein 1 antibody; D14S1460 antibody; MGC111161 antibody; NGPS antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O75531 Immunogen:Recombinant Barrier-to-autointegration factor protein (2-89AA) Raised in:Rabbit Reactivity: Tested Applications: Background:Plays fundamental roles in nuclear assembly, chromatin organization, gene expression and gonad development. May potently compress chromatin structure and be involved in membrane recruitment and chromatin decondensation during nuclear assembly. Contains 2 non-specific dsDNA-binding sites which may promote DNA cross-bridging. Exploited by retroviruses for inhibiting self-destructing autointegration of retroviral DNA, thereby promoting integration of viral DNA into the host chromosome. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:FITC Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:BANF1 Research Areas:Microbiology