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ELISA ACMSD anti-

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Quantity :50µL Clone Number: Aliases:2 amino 3 carboxymuconate 6 semialdehyde decarboxylase antibody; 2-amino-3-carboxymuconate-6-semialdehyde decarboxylase antibody; acmsd antibody; ACMSD_ antibody; Aminocarboxymuconate semialdehyde decarboxylase antibody; Picolinate carboxylase antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8TDX5 Immunogen:Fusion protein of ACMSD Raised in:Rabbit Reactivity:, Mouse Tested Applications:ELISA, IHC; ELISA:1:1000-1:2000, IHC:1:15-1:50 Background:The neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumµLation of quinolinate from ACMS. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ACMSD Research Areas:Others

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