ELISA APOC3 anti-
Quantity :50µL
Clone Number:8H12
Aliases:Apolipoprotein C-III (Apo-CIII) (ApoC-III) (Apolipoprotein C3), APOC3
Product Type:Recombinant Antibody
Immunogen Species:Homo sapiens ()
UniProt ID:P02656
Immunogen:A syntheQuantityd peptide derived from APOC3
Raised in:
Reactivity:
Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:50-1:200
Background:Component of triglyceride-rich very low density lipoproteins (VLDL) and high density lipoproteins (HDL) in plasma (PubMed:18201179, PubMed:22510806). Plays a mµLtifaceted role in triglyceride homeostasis (PubMed:18201179, PubMed:22510806). IntracellµLarly, promotes hepatic very low density lipoprotein 1 (VLDL1) assembly and secretion; extracellµLarly, attenuates hydrolysis and clearance of triglyceride-rich lipoproteins (TRLs) (PubMed:18201179, PubMed:22510806). Impairs the lipolysis of TRLs by inhibiting lipoprotein lipase and the hepatic uptake of TRLs by remnant receptors (PubMed:18201179, PubMed:22510806). Formed of several curved helices connected via semiflexible hinges, so that it can wrap tightly around the curved micelle surface and easily adapt to the different diameters of its natural binding partners (PubMed:18408013).
Clonality:Monoclonal
Isotype:Rabbit IgG
Purification Method:Affinity-chromatography
Conjµgate:Non-conjµgated
Buffer:Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Form:Liquid
Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Names:APOC3
Research Areas:Cancer; CardiovascµLar; Metabolism; Signal transduction