ELISA ARHGAP18 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:4833419J07Rik antibody; AI314906 antibody; AI843501 antibody; Arhgap18 antibody; bA307O14.2 antibody; FLJ25728 antibody; MacGAP antibody; MGC126757 antibody; MGC138145 antibody; OTTHUMP00000017190 antibody; OTTMUSP00000028606 antibody; RHG18_ antibody; Rho GTPase-activating protein 18 antibody; Rho-type GTPase-activating protein 18 antibody; SENEX antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q8N392 Immunogen:Recombinant Rho GTPase-activating protein 18 protein (389-577AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Rho GTPase activating protein that suppresses F-actin polymerization by inhibiting Rho. Rho GTPase activating proteins act by converting Rho-type GTPases to an inactive GDP-bound state (PubMed:21865595). Plays a key role in tissue tension and 3D tissue shape by regµLating cortical actomyosin network formation. Acts downstream of YAP1 and inhibits actin polymerization, which in turn reduces nuclear localization of YAP1 (PubMed:25778702). RegµLates cell shape, spreading, and migration (PubMed:21865595). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ARHGAP18 Research Areas:Signal transduction