ELISA RNF43 Antibody, HRP

Quantity :50µg Clone Number: Aliases:RNF43 antibody; E3 ubiquitin-protein ligase RNF43 antibody; EC 2.3.2.27 antibody; RING finger protein 43 antibody; RING-type E3 ubiquitin transferase RNF43 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q68DV7 Immunogen:Recombinant E3 ubiquitin-protein ligase RNF43 protein (566-697AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:E3 ubiquitin-protein ligase that acts as a negative regµLator of the Wnt signaling pathway by mediating the ubiquitination, endocytosis and subsequent degradation of Wnt receptor complex components Frizzled. Acts on both canonical and non-canonical Wnt signaling pathway. Acts as a tumor suppressor in the intestinal stem cell zone by inhibiting the Wnt signaling pathway, thereby resticting the Quantity of the intestinal stem cell zone. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:RNF43 Research Areas:Cancer; Cell biology; Immunology