ELISA ARG1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Arginase-1(Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical?marker?of hepatocellµLar differentiation in fine needle aspiration cytology and a marker?of hepatocytes and hepatocellµLar neoplasms. ARG1 is closely associated with alternative macrophage activation(PMID:12098359) and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins(PMID: 20071539).It can exsit as a homotrimer(PMID:16141327) and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia(ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2, which is critical for pathogen control.(PMID:27117406). Immunogen:arginase, liver Synonyms:ARG1, Arginase 1, liver Arginase, Liver type arginase Observed MW:25-40 kDa Uniprot ID:P05089 Reactivity:, Mouse, Rat Tested Application:ELISA, IF, WB Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200 Gene ID:383 Research Area:Signal Transduction, Metabolism