ELISA Alpha-2-macroglobulin anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Alpha-2-macroglobµLin, also known as ?2-macroglobµLin(?2M or A2M), is a protein abundant in the plasma of vertebrates and several invertebrates. A2M is an evolutionarily conserved arm of the innate immune system. It also mediates the proliferation of T cells and macrophages. A2M acts as a nonspecific protease inhibitor involved in the host defense mechanism that inactivates both endogenous and exogenous proteases, including trypsin, thrombin and collagenase. Even thoµgh A2M is produced predominantly by the liver, it may also be expressed in the reproductive tract, heart, and brain, and may have important roles in many physiological processes and medical illnesses including Alzheimer’s disease. Immunogen:alpha-2-macroglobµLin Synonyms:A2M, Alpha 2 M, alpha 2 macroglobµLin, CPAMD5, DKFZp779B086, FWP007, S863 7, ?-2M Observed MW: Uniprot ID:P01023 Reactivity: Tested Application:ELISA, IHC Recommended dilution:IHC: 1:20-1:200 Gene ID:2 Research Area:Immunology, CardiovascµLar, Metabolism, Signal Transduction