ELISA alpha-synuclein anti-

Quantity:100µg Purification:protein A+G purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Mouse Clonality:monoclonal Clone ID:5C6 Isotype:IgG1 Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Alpha-synuclein is a member of the synuclein family, which also includes beta- and gamma-synuclein. Synucleins are abundantly expressed in the brain and alpha- and beta-synuclein inhibit phospholipase D2 selectively. SNCA may serve to integrate presynaptic signaling and membrane trafficking. Defects in SNCA have been implicated in the pathogenesis of Parkinson disease. SNCA peptides are a major component of amyloid plaques in the brains of patients with Alzheimer's disease. Alternatively spliced transcripts encoding different isoforms have been identified for this gene. Immunogen:synuclein, alpha (non A4 component of amyloid precursor) Synonyms:Alpha synuclein, NACP, PARK1, PARK4, SNCA Observed MW:18 kDa Uniprot ID:P37840 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC, WB Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:500 - 1:2000 Gene ID:6622 Research Area:Neuroscience