ELISA CD3 epsilon anti-

Quantity:100µg Purification:Protein A+G purification Form:liquid Purity:?95% as determined by SDS-PAGE Host:Mouse Clonality:monoclonal Clone ID:2E4 Isotype:IgG1 Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:CD3 is a complex of proteins that directly associates with the T cell receptor (TCR). The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecµLes. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellµLar signal transduction. CD3 is considered to be a pan-T cell marker for detection of normal and neoplastic T cells. This anti-CD3 is a monoclonal antibody directed against the epsilon chain of CD3 molecµLe. Immunogen:CD3e molecµLe, epsilon (CD3-TCR complex) Synonyms:CD3, CD3 epsilon, CD3E, CD3-epsilon, T3E, TCRE Observed MW:23 kDa Uniprot ID:P07766 Reactivity: Tested Application:ELISA, WB, IHC, IF, FC Recommended dilution:WB: 1:2000 - 1:20000; IHC: 1:1000 - 1:10000; IF: 1:50 - 500 Gene ID:916 Research Area:Cancer, Immunology, Signal Transduction