ELISA Cd2ap anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, modµLates the rate of RET turnover and may act as regµLatory checkpoint that limits the potency of GDNF on neuronal survival. Controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. May play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell. May anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. Also required for cytokinesis.
Immunogen:CD2-associated protein
Synonyms:
Observed MW:70 kDa
Uniprot ID:Q9Y5K6
Reactivity:, Mouse
Tested Application:ELISA, WB, IF, IP
Recommended dilution:WB: 1:500-1:2000; IP: 1:500-1:1000; IF: 1:10-1:100
Gene ID:23607
Research Area:Signal Transduction
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