ELISA Caspase 9 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thoµght to be one of the earliest in the caspase activation cascade. This protein is thoµght to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing resµLts in mµLtiple transcript variants.This antibody can recognize the pre- and cleaved- caspase 9. Immunogen:caspase 9, apoptosis-related cysteine peptidase Synonyms:APAF 3, APAF3, Apoptotic protease Mch 6, CASP 9, CASP9, Caspase 9, CASPASE 9c, Caspase9, Caspase-9, ICE LAP6, ICE like apoptotic protease 6, MCH6 Observed MW:17kDa/36kDa/46kDa Uniprot ID:P55211 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IHC, IF Recommended dilution:WB: 1:200 - 1:200; IHC: 1:50 - 1:200; IF: 1:50 - 1:100 Gene ID:842 Research Area:Metabolism