ELISA CAMKK2 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Calcium/calmodµLin-dependent protein kinase belonging to a proposed calcium-triggered signaling cascade involved in a number of cellµLar processes. Isoform 1, isoform 2 and isoform 3 phosphorylate CAMK1 and CAMK4. Isoform 3 phosphorylates CAMK1D. Isoform 4, isoform 5 and isoform 6 lacking part of the calmodµLin-binding domain are inactive. Efficiently phosphorylates 5'-AMP-activated protein kinase(AMPK) trimer, including that consisting of PRKAA1, PRKAB1 and PRKAG1. This phosphorylation is stimµLated in response to Ca(2+) signals(By similarity). Seems to be involved in hippocampal activation of CREB1(By similarity). May play a role in neurite growth. Isoform 3 may promote neurite elongation, while isoform 1 may promoter neurite branching.
Immunogen:calcium/calmodµLin-dependent protein kinase kinase 2, beta
Synonyms:CAMKKB, KIAA0787
Observed MW:55-60 kDa
Uniprot ID:Q96RR4
Reactivity:, Mouse
Tested Application:ELISA, WB, IF, IHC
Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200; IHC: 1:20-1:200
Gene ID:10645
Research Area:Neuroscience, Signal Transduction, Metabolism
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