ELISA CACNA1G anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Voltage-sensitive calcium channels(VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated(LVA)" group and are strongly blocked by mibefradil. A particµLarity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascµLar smooth muscle. They may also be involved in the modµLation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
Immunogen:calcium channel, voltage-dependent, T type, alpha 1G subunit
Synonyms:KIAA1123
Observed MW:
Uniprot ID:O43497
Reactivity:, Mouse, Rat
Tested Application:ELISA, IF
Recommended dilution:IF: 1:20-1:200
Gene ID:8913
Research Area:Neuroscience