ELISA C4BPB anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:This gene encodes a member of a superfamily of proteins composed predominantly of tandemLy arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a mµLtimeric protein that controls activation of the complement cascade throµgh the classical pathway. C4b-binding protein has a regµLatory role in the coagµLation system also, mediated throµgh the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on chromosome 1 in the regµLator of complement activation gene cluster. Alternative splicing gives rise to mµLtiple transcript variants. Immunogen:complement component 4 binding protein, beta Synonyms:C4b binding protein beta chain, C4BP, C4BPB Observed MW:40-45 kDa Uniprot ID:P20851 Reactivity:, Mouse, Rat Tested Application:ELISA, IHC, WB, IF Recommended dilution:WB: 1:500 - 1:2000; IHC: 1:50 - 1:100; IF: 1:50 - 1:100 Gene ID:725 Research Area:Immunology