ELISA ARHGEF7 anti-
Quantity:100µg
Purification:Immunogen affinity purified
Form:liquid
Purity:?95% as determined by SDS-PAGE
Host:Rabbit
Clonality:polyclonal
Clone ID:
Isotype:IgG
Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)
Background:Acts as a RAC1 guanine nucleotide exchange factor(GEF) and can induce membrane ruffling. Functions in cell migration, attachment and cell spreading. Promotes targeting of RAC1 to focal adhesions(By similarity). May function as a positive regµLator of apoptosis. Downstream of NMDA receptors and CaMKK-CaMK1 signaling cascade, promotes the formation of spines and synapses in hippocampal neurons.
Immunogen:Rho guanine nucleotide exchange factor(GEF) 7
Synonyms:COOL1, KIAA0142, P85SPR, PAK3BP, PIXB
Observed MW:70 kDa
Uniprot ID:Q14155
Reactivity:, Mouse, Rat
Tested Application:ELISA, IP, WB
Recommended dilution:WB: 1:1000-1:4000; IP: 1:500-1:2000
Gene ID:8874
Research Area:Signal Transduction